Keeping pets healthy doesn’t end with a great diet and routine vet visits. For many dogs and cats, the right pet health supplements can fill nutritional gaps, support joints and digestion, and help them feel their best. Below, you’ll find a practical guide to choosing safe, effective options—plus our top picks to simplify your search.
What are pet health supplements?
Pet health supplements are products designed to support normal functions like digestion, joint mobility, skin and coat quality, immune response, and calm behavior. They are not drugs and aren’t intended to diagnose, treat, or cure disease. Instead, they complement a balanced diet and healthy lifestyle.
Because the supplement market is broad, quality and efficacy can vary. Work with your veterinarian before adding anything new—especially if your pet has a medical condition, takes medication, or is prone to allergies.
Signs your pet could benefit from supplements
- Joint stiffness, hesitancy on stairs, or slow rising
- Dull coat, itchy skin, excessive shedding
- Frequent tummy upsets, loose stools, or flatulence
- Stress behaviors like trembling, pacing, or vocalizing
- Age-related changes in energy, mobility, or recovery time
- Picky eating or limited diets that may leave nutritional gaps
Types of pet health supplements explained
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Probiotics and digestive enzymes
- Help maintain a healthy gut microbiome and normal stool quality
- Useful during diet changes, travel, or after antibiotics
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Omega-3 fatty acids (EPA/DHA from fish oil)
- Support skin and coat, joint comfort, heart, kidney, and cognitive health
- Often recommended for pets with seasonal skin issues or aging joints
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Joint support (glucosamine, chondroitin, MSM, green-lipped mussel)
- Promote cartilage and connective tissue health
- Ideal for large breeds, seniors, and active pets
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Multivitamins and all-in-one formulas
- Help fill everyday nutrient gaps
- May include omegas, probiotics, antioxidants, and joint ingredients
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Calming aids (L-theanine, colostrum-derived peptides, tryptophan)
- Support relaxation without sedation
- Useful for noise phobias, vet visits, travel, and routine stress
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Specialty support
- Skin/coat: biotin, zinc, omegas
- Urinary: cranberry extracts
- Liver: SAMe and milk thistle
- Always consult your vet for targeted support beyond foundational needs
How to choose pet health supplements
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Look for the NASC Quality Seal
- The National Animal Supplement Council sets rigorous manufacturing and labeling standards.
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Prioritize evidence-backed ingredients
- Examples: EPA/DHA for skin and joint support, specific probiotic strains like Enterococcus faecium, glucosamine/chondroitin for mobility.
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Match species, size, and life stage
- Many dog formulas aren’t appropriate for cats and vice versa. Dosage is weight-dependent.
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Check active ingredient amounts per serving
- Compare “per chew” or “per scoop” amounts against what your vet recommends.
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Pick a form your pet will actually take
- Chews, powders, capsules, and liquids each have pros and cons for picky eaters.
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Avoid unnecessary additives
- Minimize artificial colors, sugars, and common trigger allergens if your pet is sensitive.
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Consider your pet’s full routine
- If you already feed a diet with joint or skin support, you might not need a separate high-dose supplement.
Safety, dosing, and expectations
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Introduce one supplement at a time
- This helps you track benefits and spot any sensitivities.
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Start low and monitor
- Follow the label and your vet’s advice; many products recommend a “loading dose” period.
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Timing matters
- Probiotics may show effects in days; skin and joint support can take 4–8 weeks.
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Watch for red flags
- Vomiting, diarrhea, itching, or lethargy warrant a pause and a call to your vet.
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Store properly
- Heat and air can degrade potency. Close lids tightly and keep fish oils refrigerated if directed.
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Never substitute human supplements without veterinary guidance
- Some human products contain xylitol or other ingredients unsafe for pets.
Our top picks: best pet health supplements
We chose these standouts for quality, ingredients, and real-world usefulness across common needs like gut health, skin/coat, joints, calm behavior, and daily nutritional support.
Best probiotic for everyday gut support

Purina Pro Plan Veterinary Diets FortiFlora
Supports digestive and immune health for all breeds and sizes.
Why we like it
- A trusted probiotic to support normal digestive function during stress, diet transitions, boarding, or antibiotic use
- Convenient daily administration with a palatable format most pets accept
Pros
- Backed by veterinary professionals and widely used
- Helps maintain stool quality and digestive balance
- Easy to give; ideal for travel and post-antibiotic periods
Cons
- Primarily focused on gut support, not an all-in-one
- Pets with severe GI issues should be evaluated by a vet first
Best for
- Pets with occasional tummy upsets or during routine transitions
- Owners looking to build a foundational gut health routine
Best omega-3 for skin, coat, and overall wellness

Premium Omega 3 Supplements for Dogs
Premium omega-3 supplements for healthy skin, coat, and joint support.
Why we like it
- High-quality fish oil omega-3s (EPA/DHA) to support skin, coat luster, joint comfort, and cognitive health
- A smart addition for seasonal skin issues and aging pets
Pros
- Multi-system support in one ingredient category
- Often helps reduce excessive shedding and dryness
- Complements joint supplements for active or senior dogs
Cons
- Fishy taste can be off-putting for some pets without gradual introduction
- Must be dosed by weight; refrigeration and freshness matter
Best for
- Dogs needing skin/coat support or extra joint comfort
- Pet parents seeking a well-rounded wellness booster
Best joint support for mobility and aging

NutraMax Cosequin DS
Joint health supplement with glucosamine and chondroitin.
Why we like it
- A respected joint formula featuring glucosamine and chondroitin to support cartilage and connective tissue
- Popular choice for seniors and large breeds
Pros
- Time-tested ingredients for joint health
- Helps maintain mobility alongside weight management and exercise
- Often recommended as a first-line joint supplement
Cons
- Benefits are gradual and require consistent use
- Not a replacement for veterinary care if your pet shows pain or lameness
Best for
- Aging pets, large breeds, or active dogs showing early stiffness
- Owners building a proactive mobility plan
Best calming support for everyday stress

Why we like it
- Uses well-known calming ingredients to promote relaxation without drowsiness
- Helpful for thunderstorms, fireworks, travel, or changes in routine
Pros
- Non-sedating approach to everyday anxieties
- Can be paired with training and environmental enrichment
- Useful as-needed or daily, depending on your vet’s advice
Cons
- Response varies by pet and stressor intensity
- Behavioral issues still require training and environmental management
Best for
- Noise-sensitive pets, frequent travelers, and those adjusting to new environments
- Pairing with desensitization and enrichment strategies
Best daily multivitamin for broad coverage

Dog Multivitamin - 10 in 1 Dog Vitamins
Comprehensive multivitamin supplement for overall dog health.
Why we like it
- All-in-one style support aimed at filling routine nutrient gaps
- A practical option for busy pet parents who want a single daily step
Pros
- Consolidates multiple wellness categories into one product
- Simple routine encourages long-term consistency
- Good companion to balanced diets that need a little boost
Cons
- Not specialized; may be lighter in any one category
- Check overlap if you’re using additional single-ingredient supplements
Best for
- Healthy adult dogs needing a general wellness boost
- Families who prefer a straightforward, once-daily routine
How supplements fit with diet and lifestyle
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Feed a high-quality, complete diet
- Supplements work best as add-ons to a balanced base. If your pet’s food already targets skin and joint support, ask your vet how to layer without duplicating.
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Maintain a healthy weight
- Every extra pound strains joints and metabolism; weight management often outperforms supplements alone for mobility.
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Build a daily routine
- Consistency is key. Pair supplements with mealtime and track changes in a simple log.
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Support behavior and mobility with action
- Short, frequent walks; low-impact play; puzzle toys; and training reduce stress and help joints stay limber.
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Schedule regular checkups
- Vets can monitor progress, adjust dosing, and screen for issues that supplements can’t address.
Common mistakes to avoid
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Overlapping ingredients
- Doubling up on glucosamine or fish oil from multiple products can exceed safe limits.
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Chasing quick fixes
- Give products enough time to work and follow label directions consistently.
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Ignoring side effects
- Any new vomiting, diarrhea, itching, or lethargy needs attention. When in doubt, stop and call your vet.
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Using human products indiscriminately
- Human formulas may contain xylitol, artificial sweeteners, or doses that are unsafe for pets.
Frequently asked questions
Q: How long do pet health supplements take to work?
A: It depends on the category. Probiotics may show benefits in a few days. Omega-3s and joint supplements often need 4–8 weeks of consistent use. Calming aids can work the same day but may improve with routine use.
Q: Can I give my pet more than one supplement?
A: Yes, but coordinate with your vet to avoid overlapping ingredients and interactions. A common stack is a probiotic plus omega-3s, or a joint supplement plus omega-3s. Keep a simple schedule and introduce changes one at a time.
Q: Are human supplements safe for pets?
A: Not by default. Some human products contain unsafe ingredients for pets. Always choose pet-formulated products and confirm dosing with your veterinarian.
The bottom line
Pet health supplements can make a meaningful difference when chosen thoughtfully and used consistently. Start with your pet’s most pressing need—gut, skin/coat, joints, calm behavior, or broad wellness—then pick a high-quality product with clear dosing and proven ingredients. Track changes, stay consistent, and check in with your vet for guidance.
Ready to support your pet’s well-being? Explore the curated supplements above and build a routine that helps your best friend thrive.